Potentiometric biosensors based on ISFETs and immobilised cholinesterases

Мова статті: 
Англійська
Автор(и) статті: 
S.V.Dzyadevych, V.N.Arkhypova, A.P.Soldatkin, J.M.Chovelon, C.Martelet, N.Jaffrezic-Renault
Вихідні данні статті: 
International Journal of applied electrcomagnetics and mechanics.- Volume 23, Issue 3-4, 2006, Pages 229-244
Назва журналу: 
International Journal of applied electrcomagnetics and mechanics
Рік публікації: 
2006
Volume: 
23
Issue: 
2-3
Ключові слова: 
Cholinesterases; Glycoalkaloids; Inhibition; ISFETs; Pesticides
Ключове слово: 
Cholinesterases
Ключове слово: 
Glycoalkaloids
Ключове слово: 
Inhibition
Ключове слово: 
ISFETs
Ключове слово: 
Pesticides
This paper describes authors' achievements in the development, investigation, and application of cholinesterase biosensors based on ISFETs. Various biosensors for determination of concentrations of different toxic substances (organophosphorous and carbamate pesticides, hypochlorite, glycoalkaloids) were designed on the basis of reversible and/or irreversible enzyme inhibition effects. The main analytical characteristics of the biosensors developed have been studied under different conditions and optimal experimental protocols for toxic substances determination have been proposed. Most of these biosensors show a high reproducibility and a good operational and storage stability. A quite good correlation with results obtained through routinely used standard methods as HPLC has been shown. © 2006 - IOS Press and the authors. All rights reserved.
Назва підрозділу: 
Кафедра молекулярної біології, біотехнології та біофізики
ІНСТИТУТ ВИСОКИХ ТЕХНОЛОГІЙ Матеріали дозволено використовувати на умовах GNU FDL без незмінюваних секцій та Creative Commons Attribution/Share-Alike
Дизайн: Інститут високих технологій
Ivan Ivanov